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TauroLock™

An antimicrobial lock solution designed to prevent catheter-related complications. 

Fields of application
  • dialysis
  • oncology
  • parenteral nutrition
  • intensive care 
Active ingredients
  • 1.35 % taurolidine: broad antimicrobial activity against bacteria and fungi without generating resistance
  • 4 % citrate: anticoagulant to maintain patency 
Efficacy
  • prevention of biofilm
  • prevention of occlusion
  • prevention of infection
Package size & transport
  • single dose: 3 ml or 5 ml ampoules (10 per box)
  • multiple dose: 10 ml vials (100 per box) 
  • store between 15 and 30 °C (do not freeze)
 
Publications
Cost analysis 2023

“[TauroLock™] in the primary prevention of CRBSIs [catheter-related bloodstream infections] in patients with CIF [chronic intestinal failure] receiving HPN [home parenteral nutrition] is associated with reduced hospital costs and infection rates.” 

Williams et al. JPEN J Parenter Enteral Nutr 2023. DOI: 10.1002/jpen.2589    

Clinical study 2019

“[TauroLock™] is a safe and cost-effective method for the prevention of CRIs [catheter-related infections] in very young children.” 

Łyszkowska et al. J Hosp Infect 2019. DOI: 10.1016/j.jhin.2019.04.022   

Clinical study 2008

TauroLock as standard lock solution in long-term CVADs [central-venous access devices] significantly reduced the incidence density of CVAD-associated infections due to CoNS or MRSE.”  

Simon et al. BMC Infect Dis 2008. DOI: 10.1186/1471-2334-8-102  

Clinical study 2004

[TauroLock] is effective and safe for the prevention of CRS [catheter-related sepsis]. It may lead to a sizeable reduction in CRS incidence, even in a dialysis centre where CRS incidence is already low using heparin.” 

Betjes et al. Nephrol Dial Transplant 2004. DOI: 10.1093/ndt/gfh014